Searchable abstracts of presentations at key conferences on reproductive biology and medicine

ra0002p016 | (1) | SRF2015

Membrane potential is crucial for one of the [Ca2+]i oscillations profiles induced by progesterone in human spermatozoa

Nitao Elis Torrezan Goncalves Ramalho , Publicover Stephen J

Ca2+ signalling is critical for regulation of sperm motility. [Ca2+]i oscillations, which may underlie observed ‘switching’ of sperm behaviors, occur in human spermatozoa stimulated with progesterone. Our work aimed to investigate the potential contribution of changes in membrane potential, leading to cyclical activation of voltage dependent Ca2+-influx pathways, to [Ca2+]i oscillations. Spermatozoa we...